Whether the problem is adherence due to fear of needles (i.e. vaccines), the distractions of daily life (insulin administration and delivery) or drug-eluting stents that deliver therapy precisely in the location it is needed, innovation in drug delivery is likely to continue to improve population health, especially including in pediatric patients. All medicines have side effects, and side effects can be particularly detrimental in children. Georgia Tech investigators use many approaches to carry pharmaceutical molecules to the target locations or cells in the body and avoid other sites that may cause adverse reactions. These techniques allow children to take lower doses of medications with greater safety.
This project aims to identify therapeutic targets in pathogenic polymorphonuclear neutrophils (PMNs), an inflammatory subset that destroys airways…
